It is located on the south bank of the River Arno, just west of the Pitti Palace.

A church at the site was built about the 10th-century outside one of the gates of early walls of Florence.

It first belonged to the Monastery of San Silvestro of Nonantola, and in 1413 it was transferred to the Camaldolese Order.

Another chapel has a fresco by Giovanni da San Giovanni, depicting San Felice reviving St Massimo; the angels gathering the grapes in the painting are by Baldassare Franceschini.

Another chapel had a Madonna and Child with St Hyacinth, by Jacopo da Empoli.