San Giovanni della Pigna is a small Roman Catholic church located on Traversa Vicolo della Minerva in the rione Pigna of Rome, Italy.

The church was made a cardinalate deaconry by Pope John Paul II in 1985.

Initially a church dedicated to Saints Eleuterio and Ginnasi Martyrs was located here.

In ruinous state, it was granted by Pope Gregory XIII to the 'Archconfraternity of the Pietà verso il carcerati, led by the Jesuit Giovanni Talier.

Pope Sixtus V granted them the right to pardon one prisoner under the death sentence.