Sansare is a municipality in the El Progreso department of Guatemala.

Sansare is known for its annual bicycle race, the "Carretera Valle del Sare".

[1] The municipality and the valley are named after the sare tree (Acaciella angustissima).

[2] The area was already settled by Mayans, associated with the cultures of Copán and Quiriguá, when the Spanish arrived.

The valley was mentioned as early as 1769 in Spanish records, and the municipality was included in those mentioned in the creation of the department of Zacapa in 1871.