Santa Ana is a municipality in the Honduran department of La Paz, known for its high crime rate.

[citation needed] At the time of the 2013 Honduras census, Santa Ana municipality had a population of 11,777.

Of these, 95.56% were Indigenous (95.46% Lenca), 4.25% Mestizo, 0.13% Black or Afro-Honduran and 0.06% others.

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