Santiago de Puringla is a municipality in the Honduran department of La Paz.

The municipality is situated on a plain bordered by the River Puringla.

On 5 September 1921, as an act of celebration of the centenary of Independence, it was agreed to change the name to its current form.

[1] In April 2020, the municipality suffered fires in large parts of Delicias.

At the time of the 2013 Honduras census, Santiago de Puringla municipality had a population of 16,182.