Santa Barbara dei Librai[1] is a small Roman Catholic church in Rome, Italy.

Today it now considered within the rione of Parione, near the Campo de' Fiori.

Inscriptions inside claim that the church was established by Giovanni di Crescenzio de Roizo and his wife Rogata, who was a senator of Rome in the second century.

The statue of St Barbara over the door was sculpted by Ambrogio Parisi, and the angel painted on a wall is attributed to Guido Reni.

The church has paintings by Luigi Garzi; a fresco of St Saba by Giovanni Battista Brughi, pupil of Baciccio, in the chapel of Specchi; and frescoes by Francesco Ragusa and Domenico Monacelli.