Santa Catalina is a village in the Soriano Department of western Uruguay.

The village is located on Route 2, about 15 kilometres (9.3 mi) northwest of Cardona and 12 kilometres (7.5 mi) southeast of José Enrique Rodó.

The railroad track Montevideo - Mercedes passes through the town.

On 19 December 1940, the status of the populated nucleus here was elevated to "Pueblo" (village) by the Act of Ley Nº 9.985.

[1] Previously, it had been the head of the judicial section "Arroyo el Medio".