[1] The campus and hospital were founded at its present location in 1876 by Dr. Benjamin Cory, the Director of Public Health.

The current campus continues to sit at the very same spot where the original hospital was constructed in the 19th century.

It is designated a primary stroke treatment center by the Joint Commission on Accreditation of Health Organizations.

Residency programs operated by Santa Clara Valley Medical Center include internal medicine, obstetrics/gynecology, radiology, and pharmacy.

The HealthGrades website contains the clinical quality data for Santa Clara Valley Medical Center, as of 2018.