[3] Santa Josefa is located at 7°59′N 126°02′E / 7.98°N 126.03°E / 7.98; 126.03, making it the province's most southerly settlement.

According to the Philippine Statistics Authority, the municipality has a land area of 341.8 square kilometres (132.0 sq mi) [5] constituting 3.42% of the 9,989.52-square-kilometre- (3,856.98 sq mi) total area of Agusan del Sur.

Santa Josefa is classified as Type II climate which has no dry season but with pronounced maximum rain period occurring from December to January.

[3] The population density was 77 inhabitants per square kilometre (200/sq mi).

Poverty incidence of Santa Josefa Source: Philippine Statistics Authority[13][14][15][16][17][18][19][20] Santa Josefa's main products are rice and corn.