Satiety (/səˈtaɪ.ə.ti/ sə-TYE-ə-tee) is a state or condition of fullness gratified beyond the point of satisfaction, the opposite of hunger.
These receptors then signal through afferent vagus nerve fibers to the hypothalamus, increasing satiety.
In addition, as the food moves into the duodenum, duodenal cells release multiple substances that affect digestion and satiety.
[4] Cholecystokinin (CCK) is gut peptide produced by the duodenum in response to fat and proteins.
CCK has the effect of slowing gut motility and increasing satiety as well as activating release of pancreatic digestive enzymes and bile from the gallbladder.