Savanna Army Depot was a 13,062-acre (52.86 km2) installation, located on the eastern bank of the Mississippi River, in Carroll and Jo Daviess counties, around seven miles (11 km) north of Savanna, Illinois.

It was opened in 1917 as a proving and testing facility for weapons developed at Rock Island Arsenal.

The U.S. Environmental Protection Agency (EPA) listed the depot as a Superfund site in 1989.

On September 26, 2003, the United States Department of Defense agreed to transfer 9,404 acres (38.06 km2) of land to become the Lost Mound Unit of the Upper Mississippi River National Wildlife and Fish Refuge.

12 was transferred to the United States Army Corps of Engineers and a small part to the Illinois Department of Natural Resources.