The show's premise originated with Malcolm MacRury and Morwyn Brebner, who are both credited as creators and executive producers.

The protagonist of the show is Dr. Alex Reid (Erica Durance), a doctor whose fiancé, Dr. Charles Harris (Michael Shanks), is in a coma after a car accident while on his way to their wedding.

Reid also works alongside Dr. Shahir Hamza (Huse Madhavji), a neurosurgeon, Dr. Maggie Lin (Julia Taylor Ross), a third year surgical resident on rotation in the General Surgery department, Dr. Gavin Murphy (Kristopher Turner), a psychiatry resident, Dr. Zachary Miller (Benjamin Ayres), the ER doctor, OR nurse Victor Reis (Salvatore Antonio), Dr. Tom Reycraft (K. C. Collins), Dr. Melanda Tolliver (Glenda Braganza), and Dr.

On November 7, 2013, CTV ordered a third season of Saving Hope that consisted of eighteen episodes and aired in 2014.

[21] On November 10, 2014, CTV ordered a fourth season of Saving Hope that consisted of eighteen episodes,[22] and premiered on September 24.

"[42] The Chicago Sun-Times's Lori Rackl said the series "has some fun, clever and emotion-stirring moments, but they’re handicapped by cheesy montages and one too many scenarios designed to remind us of the importance of having hope.

"[43] Alan Sepinwall of HitFix called Charlie Harris' "spirit walk" around the hospital "an interesting solution to the problem of telling stories we've seen a million times before.

"[44] The San Francisco Chronicle's David Wiegand called the series "a lukewarm stew of ideas from other shows... and films... with stock characters and situations that occasionally jerk a demi-tear or two, but with absolutely no authenticity.