[1] The road was built on land owned by Trinity College and named after one of its professors, Sedley Taylor (1834–1920).
[5] Alcantara, a house near the South end of the street, is grade II listed.
Speed reduction measures including "gates" (limiting the road to half-width) and humps were installed in 2009.
In 2012, residents unsuccessfully opposed plans for a new sports pavilion in the land to the West of the road.
[10] Sedley Taylor Road is mentioned in Tom Sharpe's book Grantchester Grind as the home of the widow of local solicitor, Waxthorne.