[6] This protein binds to the serum response element (SRE) in the promoter region of target genes.

[7][8] SRF is important during the development of the embryo, as it has been linked to the formation of mesoderm.

[9][10] In the fully developed mammal, SRF is crucial for the growth of skeletal muscle.

[12] Interaction of SRF with other proteins such as myocardin or Elk-1 may enhance or suppress expression of genes important for growth of vascular smooth muscle.

[13] Serum response factor has been shown to interact with: This article incorporates text from the United States National Library of Medicine ([1]), which is in the public domain.