Simple Modular Architecture Research Tool (SMART) is a biological database that is used in the identification and analysis of protein domains within protein sequences.
[1][2] SMART uses profile-hidden Markov models built from multiple sequence alignments to detect protein domains in protein sequences.
The most recent release of SMART contains 1,204 domain models.
[4] The database is hosted by the European Molecular Biology Laboratory in Heidelberg.
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