Sint Kruis is a village in the Dutch province of Zeeland.

It is located about 4 km east of Aardenburg, in the municipality of Sluis.

The village was first mentioned in 1270 as "jndie prochia van sint crues", and refers to the Holy Cross parish of the Saint Bavo's Abbey in Ghent.

[4] The area around Sint Kruis was inundated in 1584 to thwart the progress of the Spanish Army.

[5] Sint Kruis was home to 613 people in 1840.