They can be formed by the neutralization of acids with sodium hydroxide.
Sodium salts can be categorized into: In pharmaceutical technology acidic pharmaceutical substances are often converted into sodium salts, because they are more stable, more soluble or membrane-permeable (bioavailable) than the base compound.
Examples of such sodium salts are (selection): Bispyribac, bithionol, bosentan, brequinar, bromfenac, Cefmenoxime, ceftiofur, citicoline, cromolyn, diclofenac, Flucloxacillin, fosinopril, Mordant brown 33, naproxen, Netobimin, ozagrel, pantoprazole, pemetrexed, secobarbital, sitamaquin, sitaxentan, sulfamiderazin, sulfapyridine, sulfaquinoxaline, sulfathiazole, sulfazecin, thiamylal and mesna.
Herbicides are often used as sodium salts for the reasons discussed above.
Sodium salts of certain aromatic sulfonic acids—particularly naphthalenesulfonic acid—are used in the preparation of azo dyes.