Sophia Eleonore of Hesse-Darmstadt (7 January 1634 in Darmstadt – 7 October 1663 in Bingenheim, now part of Echzell), was Landgravine of Hesse-Darmstadt by birth and by marriage Landgravine of Hesse-Homburg.

In Darmstadt on 21 April 1650 Sophia Eleonore married to her cousin, Landgrave William Christoph of Hesse-Homburg (1625–1681).

On the occasion of her wedding, her father gave her the district of Castle Bingenheim.

William Christoph preferred Bingenheim to his castle in Homburg, so the family mostly lived in Bingenheim and William Christoph was sometimes called the Landgrave of Hesse-Bingenheim.

Sophia Eleonore gave birth to 13 children, but only 5 survived infancy:[1] She died in Bingenheim aged 29, following complications in her last childbirth.