Prior to European settlement, what is now South Penrith was home to the Mulgoa people who spoke the Darug language.

The park is named after the Penrith region's most famous early settler, Sir John Jamison (1776–1844), of Regentville House.

The nearest railway station is at Penrith on the Western Line of the Sydney Trains network.

[1] At a local government level, South Penrith is part of the south ward of Penrith City Council, represented by Jim Aitken, Mark Davies, Karen McKeown, Kathryn Presdee and Joshua Hoole.

At the state level, it is part of the Electoral district of Penrith, represented by Liberal MP Stuart Ayres.

Federally, it is part of the Division of Lindsay, represented by Liberal MP Melissa McIntosh.