Prior to European settlement, what is now Werrington was home to the Gomerrigal-Tongarra people who spoke the Darug language.

They hunted kangaroos and emus for meat, and gathered yams, berries and other native plants.

[2] They built a house, which they named Werrington, and farmed the surrounding estate until 1865, when Robert Lethbridge died.

Werrington, which still stands in Rugby Street, was leased to New South Wales premier Henry Parkes between 1860 and 1872.

[15][16] Werrington is served by the Great Western Highway and the M4 Motorway (Kent Road exit).

[17] At a local government level, Werrington is part of the north ward of Penrith City Council, represented by Richard Fowler (Mayor of Penrith).At the state level, it is part of the Electoral district of Londonderry, represented by Labor Party member Prue Car.Federally, it is part of the Division of Lindsay, represented by Liberal Party member Melissa McIntosh.