[10] The re-routing of US 80 down US 80 Truck sparked widespread controversy across the state of Arizona, due to the heavy modifications needed to be made to Fremont Street, which was the location of several historic buildings.

This was because the modifications included altering the appearance of several historic buildings and structures along Fremont Street to make room for a wider four lane highway.

[11] U.S. Route 80 (Alternate) in El Paso ran southbound from the junction of Farm To Market Road 260 and U.S. 80, following Doniphan Drive through the former community of White Spur[13] (now part of Northwest El Paso).

[14] U.S. 80 (Alternate), and Paisano drive then followed the tracks of the Atchison, Topeka and Santa Fe Railway along the eastern bank of the Rio Grande until Union Station in Downtown El Paso.

Continuing east for 35 miles, the route turned southeast, traversing the Metcalf Gap, a pass through the low range of hills and mesas known as the Palo Pinto Mountains, before heading east for 36 miles to Weatherford.

[15] Bypassing the main route, which continued east from Abilene through Eastland, Cisco, and Strawn to Weatherford, the alternate route allowed travelers to pass near historic Fort Griffin, traverse the unique topography of the Western Cross Timbers, and take the waters in the town of Mineral Wells, known for its mineral-rich springs.

The section of U.S. 80 N between Albany and Abilene would be given its current designation of Texas State Highway 351 in August 1943.

It follows the route of LA 799, allowing truck traffic to avoid the downtown part of Gibsland.

It follows the route of LA 798-1, allowing truck traffic to avoid the main street of Arcadia.

South of Voeglin Avenue, the road crosses a pair of railroad lines then makes a southeast curve just before the intersection with J.L.

The concurrency with SR 22 ends at Dallas Avenue, when it makes a right turn to head west.

approaches the Edmund Pettus Bridge, the site of the infamous police attack on the Selma to Montgomery marches.

The road curves to the southeast as it crosses a railroad line and serves as the eastern terminus of Roosevelt Avenue at the same time.

[21][22][23][24] The Truck route begins at the intersection of Broad Street and Highland Avenue in Selma.

[21] US 80 Truck continues east on Highland Avenue, passing a junction with Dallas County Route 65 at Marie Foster Street.

US 80 Truck passes an intersection with SR 140 that also serves as the western terminus of said state highway.

US 80 Truck crosses the Alabama River into West Selmont, intersecting with Old Montgomery Highway (CR 56).