The Church of St. Catherine of Genoa is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York, located at 504 West 153rd Street, between Broadway and Amsterdam Avenue in the Hamilton Heights neighborhood of Manhattan, New York City.

[4] The AIA Guide to New York City calls the gabled church "a unique star" of the Hamilton Heights neighborhood.

[1] The design is particularly marked by the building's wide crow-stepped gable and ogee-headed openings, very similar to Poole's more compact Our Lady of Good Counsel (1892), and a predecessor to Poole's grander-scaled St. Thomas the Apostle in Harlem, now closed.

The facade is "golden-hued brick", and the building features a "deep porch sheltered by a bracketed entryway.

John J. Brady had a four-story brick schoolhouse built at 508-510 West 153rd Street to designs by Jules Lewis known as the Annex, it opened in 1938.