The school's deaf and hearing teachers use ASL as a method of instruction, but the majority use is Simultaneous Communication.

While based in the Catholic Archdiocese of Cincinnati, St. Rita School works to meet the needs of Deaf and hard of hearing and students with special communication needs.

St. Rita's is one of the first schools in the country to develop a program for dyspraxic children, sometimes referred to as "global" apraxia.

The school's Montessori pre-school program is designed to meet the development needs of hearing and deaf children, starting at 3 years of age.

In 1962, the high school division petitioned the Greater Catholic League to compete in football at the reserve level.