It was started as an Anglo-Indian school in the 16th century, run under the management of Latin Diocese of Kannur.

In the early 16th century, an Anglo-Indian school was established as part of the Holy Rosary Church.

Moorkoth Kumaran, a short story writer of early Malayalam literature, the municipal vice chairman of Thalassery during that period, and an eminent person in the social and political fields, was the first assistant until 30 April 1930.

101 prominent citizens presented a memorandum in front of Father Rodrigs.

Father George Pathiyil was appointed as the headmaster of Saint Joseph's High School in 1952.