[1] [2] [3] [4][5][6] The overarching aim is to understand the basic mechanisms that allow exogenously delivered stem cells, gene therapy vectors and/or exosomes to create an environment that preserves damaged axons or prevents neurons from dying.

He is best known for having provided compelling evidence in support of the feasibility and efficacy of advanced stem cell therapies in rodent and non-human primate models of inflammatory neurological diseases, including multiple sclerosis.

He earned an M.D., a full residency in Neurology and a Ph.D. in Experimental Neurosciences from the University of Siena, Italy (joint with San Raffaele Scientific Institute, Milan), under the mentorship of Gianvito Martino in 2004.

[7][9][21][12] The overarching aim is to understand the basic mechanisms that allow exogenously delivered stem cells, gene therapy vectors and/or exosomes[22][23][24][8][25] to create an environment that preserves damaged axons or prevents neurons from dying.

[10][27][13][28] In addition to his positions in the Department of Clinical Neurosciences at the University of Cambridge, Pluchino serves as Chair of the Scientific Advisory Board at ReNeuron lcc.