Streptomyces clavuligerus

Streptomyces clavuligerus is a species of Gram-positive bacterium notable for producing clavulanic acid.

[1] S. clavuligerus ATCC 27064 (NRRL 3585, DSM 738) was first described by Higgens and Kastner (1971), who isolated it from a South American soil sample.

[2] Its name refers to the shape of its spore-bearing hyphal branches: from the Latin clavula 'little club' and igerus 'bearing'.

[6] For S. clavuligerus ATCC 27064, a teleocidin biosynthetic gene cluster was identified in early isolates held at ATCC, apparently missing from later isolates used for industrial production of clavulanic acid.

[10] Alvarez-Alvarez, R.; Rodriguez-Garcia, A.; Santamarta, I.; Perez-Redondo, R.; Prieto-Dominguez, A.; Martinez-Burgo, Y.; Liras, Paloma (May 2014).