[1] The supramarginal gyrus is part of the somatosensory association cortex, which interprets tactile sensory data and is involved in perception of space and limbs location.

[2][3] The right-hemisphere supramarginal gyrus appears to play a central role in controlling empathy towards other people.

When this structure is not working properly or when individuals have to make very quick judgements, empathy becomes severely limited.

[4] Research has shown that disrupting the neurons in the right supramarginal gyrus causes humans to project emotions on others, inhibiting the ability to be empathetic.

[5][verification needed] Both the left and right supramarginal gyri of healthy, right-handed individuals are shown to be active when making phonological word choices.