259292387348ENSG00000278111ENSG00000262525ENSG00000226761ENSMUSG00000059382P59540Q7M721NM_176887NM_207023NP_795368NP_996906Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.

[8] hTAS2R46 is a bitter receptor broadly tuned to sesquiterpene lactones, related clerodane diterpenoids, labdane diterpenes and more.

TAS2R46 was shown to be expressed in other tissues in the human body apart from the oral cavity including human bone marrow stromal-derived cells (MSC) and their relatives, vascular smooth muscle cells (VSMC).

Strychnine even makes an appearance in the famous Agatha Christie novel The Mysterious Affair at Styles.

TAS2R46 was associated with Inflammatory Bowel Disease[12] Obtained from[9] Known mutations of TAS2R46 include the following:[9] This article incorporates text from the United States National Library of Medicine, which is in the public domain.