702121419ENSG00000008196ENSMUSG00000025927Q92481Q61313NM_003221NM_001025305NM_001286340NM_009334NP_003212NP_001020476NP_001273269NP_033360Transcription factor AP-2 beta also known as AP2-beta is a protein that in humans is encoded by the TFAP2B gene.

[5][6] AP-2 beta is a member of the AP-2 family of transcription factors.

AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences.

[7] Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.

[7] This article incorporates text from the United States National Library of Medicine, which is in the public domain.