5550429820ENSG00000127863ENSMUSG00000060548Q9NS68Q9JLL3NM_001204458NM_001204459NM_018647NM_148957NM_001354985NM_001164155NM_013869NP_001191387NP_001191388NP_061117NP_683760NP_001341914NP_001157627NP_038897Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY is a human gene.
It has been shown to interact with TNF receptor associated factor (TRAF) family members, and to activate c-Jun N-terminal kinases (JNK) signaling pathway when overexpressed in cells.
This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development.
Alternatively spliced transcript variants encoding distinct isoforms have been described.
[5] This article incorporates text from the United States National Library of Medicine, which is in the public domain.