Tabakhane is a historic neighborhood, quarter, Mahalla, or parish of central Nicosia, Cyprus,[2][3][4] named after the tannery which formerly existed just outside the city walls, near Paphos Gate.

[5] According to the survey reported by George Jeffery (government architect) [6] Tabakhane formerly extended as far west as Paphos Gate and was therefore close to the old site of the Tannery, which is now occupied by the Municipal Garden.

[7] These streets have subsequently been renamed:[12] The tannery was originally located just outside the Paphos Gate, now the site of the Municipal Gardens.

Tanning, like butchery, requires the use of sharp knives, and Under Ottoman rule, it was a Muslim monopoly.

The tanners worked within the framework of a traditional guild and had their own quarter of the city, Tabakhane.