The enzyme tartronate-semialdehyde synthase (EC 4.1.1.47) catalyzes the chemical reaction This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds.

The systematic name of this enzyme class is glyoxylate carboxy-lyase (dimerizing tartronate-semialdehyde-forming).

Other names in common use include tartronate semialdehyde carboxylase, glyoxylate carbo-ligase, glyoxylic carbo-ligase, hydroxymalonic semialdehyde carboxylase, tartronic semialdehyde carboxylase, glyoxalate carboligase, and glyoxylate carboxy-lyase (dimerizing).

This enzyme participates in glyoxylate and dicarboxylate metabolism.

This EC 4.1 enzyme-related article is a stub.