Its western terminus is in west Knox County at SR 131 (Lovell Road/Ball Camp-Byington Road).

It goes east through suburban areas to have an intersection with Cedar Bluff Road, which leads south to an interchange with I-40/I-75 (Exit 378).

It continues east through Suburban areas, where it enters Knoxville and has intersections with Gallaher View Road and Weisgarber Road before passing through industrial areas, where the median widens to the point that there are businesses inside of the median.

The 2 halves of the roadway rejoin each other shortly before having an intersection with Ed Shouse Road, which leads to I-640/I-75 (Exit 1).

The highway then passes through a business district before coming to an end at an intersection with SR 62 (Western Avenue), just east of downtown.