[1] Species within this genus are primarily known for their ubiquitous presence in various habitats, including soil, decaying plant matter, and aquatic environments.

[1] Initially, up until the turn of the 20th century, nine different aquatic species were distinguished based on the observable characteristics of their spores.

Although Tetracladium species have been extensively studied, their sexual reproduction process continues to elude researchers.

Some recently described species rely on subtle morphological or developmental differences, which may only be apparent under specific laboratory conditions.

[3] Currently, the genus comprises 11 recognized species, with nine described from aquatic habitats and three from terrestrial environments, identified using DNA sequencing and morphological characteristics.