SH 182's western terminus is at U.S. Highway 69 in Alba.

[2] The highway travels east through Wood County along the southern shoreline of the Lake Fork Reservoir.

The highway's eastern terminus is at its intersection with SH 154 west of Quitman.

[5] SH 182 was designated on November 30, 1932 along its current route.

The route was part of SH 42 before March 19, 1930, but was erroneously omitted from the highway log issued on that date.