Thermosome

A thermosome is a group II chaperonin protein complex that functions in archaea.

[2] A thermosome has two rings, each consisting of eight subunits, stacked together to form a cylindrical shape with a large cavity at the center.

The complex consists of two subunits[dubious – discuss] that alternate location within its two rings.

The main difference, however, lies in the existence of a helical protrusion in the thermosome which composes of a built-in lid of the hydrophilic cavity.

Under lower or high pH conditions, these residues are charged and repelled each other which negatively affect thermal stability.