[1][2] Other solvents for producing tinctures include vinegar, glycerol (also called glycerine), diethyl ether and propylene glycol, not all of which can be used for internal consumption.
For individuals who choose not to ingest alcohol, non-alcoholic extracts offer an alternative for preparations meant to be taken internally.
Tinctures are often made of a combination of ethyl alcohol and water as solvents, each dissolving constituents the other is unable to, or weaker at.
A downside of using alcohol as a solvent is that ethanol has a tendency to denature some organic compounds, reducing or destroying their effectiveness.
Ether and propylene glycol based tinctures are not suitable for internal consumption, although they are used in preparations for external use, such as personal care creams and ointments.