Topolnitsa (Bulgarian: Тополница) is a reservoir in the Sredna Gora mountain, western Bulgaria.

It was built on the Topolnitsa river just south of the village of Muhovo.

The main purpose of the Topolnitsa Dam is to irrigate agricultural lands in the Upper Thracian Plain.

There is a small hydro power plant.

It is a good place for fishing with the abundance of carp, rudd, perch and other species of freshwater fish.