Toxoprion (Ancient Greek for "bow saw") is an extinct genus of eugeneodont holocephalans whose fossils are found in marine strata from the Early Carboniferous until the Late Permian near Eureka, Nevada.

[1] Toxoprion was one of the many Carboniferous eugeneodonts which bore a palatoquadrate fused to its skull or reduced in other forms, and had its heavily serrated teeth grow outwards on the symphysis of the lower jaw similar to a rounded saw.

[2] Despite its jaw showing similarities to another eugeneodont, Helicoprion, the tooth row of Toxoprion does not coil back on itself, as seen in Helicoprion, but instead forms a downward curved tooth whorl similar to Campyloprion, Lestrodus, and Edestus.

[3] The genus acquired its name from the Greek word τόξο (tóxo), from the bow-shaped jaw on which the teeth of the creature were arranged, and πριόνι (prióni), for the number of triangular serrated teeth it had.

While originally suggested to be a member of the genus Helicoprion, it was later shown to be a distinct animal.