Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
[2][3][4][6] In addition, although it is not approved for clinical or veterinary use, trenbolone enanthate is sometimes sold on the black market under the nickname Trenabol.
[11] The bradykinin peptide is well known to promote a cough reaction associated with ACE inhibitor medications prescribed for hypertension.
[13] At least one study in rats has shown trenbolone to cause gene expression of the androgen receptor (AR) at least as potent as dihydrotestosterone (DHT).
This evidence tends to indicate trenbolone can cause an increase in male secondary sex characteristics without the need to convert to a more potent androgen in the body.
[2][3][4][6] Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone.
[citation needed] Trenbolone and 17-epitrenbolone are both excreted in urine as conjugates that can be hydrolyzed with beta-glucuronidase.
[2][3][4][28] Some bodybuilders and athletes use trenbolone hexahydrobenzylcarbonate and other esters (acetate, enanthate) for their muscle-building and otherwise performance-enhancing effects.