[2] It is located 30 miles (48 km) north of Yuma east of the Colorado River in an area called the Lower Colorado River Valley.

It is a 15-mile (24 km) stretch of ridgeline of the rugged desert Trigo Mountains and is adjacent to historical mines, the Red Cloud and Hart Mine.

The northeast boundary of the wilderness borders the Yuma Proving Ground.

This ecoregion portion of the Colorado River Valley, of two waterfowl refuges, and mountains is associated with the US Army installation of the Yuma Proving Grounds.

A major mountain system lies just eastwards, the Kofa National Wildlife Refuge, (with its adjacent Wilderness Area).