Trinder glucose activity test

The Trinder reagent, named after P. Trinder of the Biochemistry Department of the Royal Infirmary in Sunderland (see the article listed in further reading), comprises an aminoantipyrine (such as 4-aminoantipyrine) and phenol (p-hydroxybenzene).

[1][2] The Trinder reaction is the reaction between hydrogen peroxide and the phenol and aminoantipyrine to form a quinone (quinoneimine), catalyzed by the presence of a peroxidase (such as horseradish peroxidase).

[3] Diagnostic kits containing the Trinder reagent are available, including one from Sigma-Aldrich.

[2] The Stanbio Single Reagent Glucose Method is based upon the Trinder technique.

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