Today, Trinity-St. Paul's has a reputation for being an activist church on a number of social justice issues.

The church has strongly advocated for same-sex marriage, fair trade and improved conditions for the homeless.

Former United Church moderator and noted activist Bill Phipps was minister from 1974 to 1983.

Cheri DiNovo, a former Ontario New Democratic Party politician, became minister effective February 4, 2018.

In 1980, it merged with St. Paul's-Avenue Road United Church, which was itself a merger of St. Paul's Methodist and Avenue Road Presbyterian.