Tris(2-pyridylmethyl)amine (abbreviated TPMA or TPA) is an organic compound with the formula (C5H4NCH2)3N.

It is a tertiary amine with three picolyl substituents.

It is a white solid that is soluble in polar organic solvents.

It is a ligand in coordination chemistry.

The ligand is prepared by the alkylation of 2-picolylamine by picolyl chloride:[1] TPMA is a tripodal ligand, often used to simulate the coordination environment within some proteins.