Tuscola High School is a public senior high school located in Waynesville, North Carolina, United States, about 30 miles (48 kilometers) west-southwest of Asheville.

On September 30, 1963, the joint boards of education recommended that the schools of Haywood County consolidate.

The construction of these new schools was to be financed by a $2.5 million bond, along with additional state and local funds.

In order to make travel more reasonable for residents of Crabtree and Fines Creek, the location of the high school was moved from West Waynesville to an East Waynesville community near Lake Junaluska known as Tuscola.

However, the school was named Tuscola, after the East Waynesville community in which it was built.