Twiggs Academy competes in baseball, men's and women's basketball, football, softball, and track.

[6] Twiggs Academy has won GISA Championships:[7] Although Twiggs Academy competes in GISA in all other sports, the Trojans play football in the Independent Christian Schools of Georgia and Alabama, a Christian league consisting of teams from Georgia, Florida, and Alabama.

Twiggs Academy competes in GISA literary competition including events such as oral interpretation, extemporaneous speaking, trio, quartet, solo, and essay.

[10] A large gymnasium; a modern media center and science lab; a library; baseball, softball, and football fields; and a cafeteria are located on campus.

[11] Twiggs Academy graduates fill many local offices in Twiggs County, Jeffersonville, Danville, and other municipalities throughout the State of Georgia, including coroner, probate judge, tax assessor, tax commissioner, clerk of court, city councilmember, mayor, and assistant district attorney.