U.S. Route 70 Alternate (US 70A) was established around 1953, replacing the old mainline US 70 through Pine Level.

Originally, it started in Smithfield along US 301 going north to Selma, then east through Pine Level to its eastern terminus near Princeton.

In the early 1970s, it was rerouted east from Selma to Wilson's Mills along formerly secondary roads.

In 1993, it was truncated at its current western terminus when US 70 was rerouted along the Wilson Mills-Selma route.

The route was created by the Arkansas State Highway Commission (ASHC) on August 2, 1962, following construction of a US 70 bypass around town to the south.

The highway becomes a freeway near the Gulpha Gorge Campground at Hot Springs National Park.

is a business loop and former segment of mainline US 70 in Huntingdon, Tennessee, which also shares a hidden concurrency with SR 1.

The route runs along West Main Street until reaching the heart of town where it encounters and off-center roundabout centering on the historic Carroll County Courthouse, shared in an overlap with TN Bus 22.

is a business loop in Camden, which also shares a hidden concurrency with SR 391.

is a 3.4 miles (5.5 km) business route that replaced US 70 through downtown Lebanon, via Main Street.

was established in 1960 from a renumbering of US 70A, this business loop goes through downtown Morganton via Union and Meeting Streets.

[16] In November 2023, AASHTO approved the eliminating part of US 70 Bus., between Garner and Clayton, and rerouted mainline US 70 along its former alignment through there.

was established in 1960 from a renumbering of US 70A, this business loop goes through downtown Kinston via Vernon Avenue and Queen Street.

In an effort to make the area less confusing, NCDOT opted for the Bypass designation as opposed to another business loop.

U.S. Route 70 Alternate (US 70A) was established in 1948 after US 70 was rerouted south bypassing Hickory.

In 1957, US 70A was extended east, replacing US 70 through High Point (Westchester Drive, Lexington Road and Greensboro Road), Jamestown (High Point Road), Greensboro (Lee, Spring Garden, Aycock, Fairground and Market Streets), Burlington, Mebane and Efland; which was US 70A's apex, at nearly 66 miles (106 km) long.

Around 1963, US 70A eastern terminus was truncated at O. Henry Boulevard; everything east from that point was reverted to US 70.

In 1969, US 70A was rerouted to use Lee Street to Murrow Boulevard, then north to Summit Avenue.

Around 1991, the entire route was decommissioned, most of it becoming secondary, except for English Road continuing as NC 68.

[25][32] U.S. Route 70 Alternate (US 70A) was established in 1934 as a renumbering of NC 10A, which traveled from Chapel Hill Street, in downtown Durham, southeast on Main Street and Angier Avenue, to Miami Boulevard, in Bethesda.

Starting at Roxboro Road, it traveled through downtown Durham via Main, Alston, and Angier Avenue; at Bethesda, it goes south along Miami Boulevard and Chapel Hill Road into Cary, then going east along Western Boulevard into Raleigh, where it connects with Boylan Avenue, South, Fayetteville, Lenoir and finally East Street, where it reconnects with US 70.

By 1952, US 70A was rerouted west from Bethesda onto and overlapping with US 70 to Holloway street, where it went into the downtown area along Roxboro, Pettigrew, Chapel Hill, Duke, Main, and 9th streets before connecting onto Hillsborough Road.

US 70A then continued on Bennett Memorial Drive before reconnecting again with US 70; Angier Street was downgraded to a secondary road (SR 1926).

[29] In 1960, US 70A was replaced by US 70 Business, except for Bennett Memorial Drive, which was downgraded to secondary road (SR 1313).

was a business route of US 70 in Hugo, Oklahoma which is 5 miles (8.0 km) long.

The route was decommissioned in 2019 to eliminate highway traffic from passing through Hugo.

U.S. Route 70C (US 70C, the "C" for "City", i.e., a business loop) formerly ran between what is now Interstate 30 (I-30) exits 116 (Sevier & South Streets) and 118 (Congo Road) in Benton, Arkansas.

The business loop was removed in 1994 when US 70 moved back to its original route through Garner.

possibly appeared soon after the mainline US 70 rerouting on new bypass route north of Beaufort in January 2018, confirmed with Google Street View imagery from July 2018.

U.S. Highway 70 Temporary was a designation for a route between Kirby and Lockesburg, Arkansas while a new alignment of US 70 was under construction.