UFC 269: Oliveira vs. Poirier was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on December 11, 2021, at the T-Mobile Arena in Paradise, Nevada, part of the Las Vegas Metropolitan Area, United States.

[12] A flyweight bout between former title challenger Alex Perez and Matt Schnell had been rescheduled for UFC Fight Night: Brunson vs.

[16] A women's flyweight bout between Montana De La Rosa and Maycee Barber was expected to take place at the event.

[17] However, De La Rosa pulled out of the fight in early October citing injury and she was replaced by Erin Blanchfield.

[23] A heavyweight bout between Augusto Sakai and Tai Tuivasa was scheduled for UFC Fight Night: Vieira vs. Tate, but it was scrapped due to visa issues.