[3] A bantamweight bout between Cory Sandhagen and former UFC Lightweight Champion Frankie Edgar took place at the event.

[11] In turn, Dvalishvili was forced to pull out from the bout in mid January due to his COVID-19 recovery and he was replaced by Andre Ewell.

[22] However, in the weeks leading up to the fight, Montaño was pulled from the event due to undisclosed reasons and replaced by Joselyne Edwards.

[24] However, Arce was removed from the event in late January due to undisclosed reasons and replaced by Martin Day[25] The bout took place at featherweight.

[14] Alex da Silva Coelho was expected to face Devonte Smith in a lightweight bout at this event.

[29] However, Bondar withdrew during fight week due to undisclosed reasons and was replaced by Jerome Rivera, with their bout taking place at featherweight.

[30][14] They were previously scheduled to meet at a planned date of January 30 in a flyweight bout, but the event never materialized and the pairing was cancelled.