The promotion had previously been partnered with Reebok since 2014, before signing a deal with Venum in July 2020 that would be made effective April 2021.

[3][4] A middleweight bout between former UFC Welterweight Championship challenger Darren Till and Marvin Vettori was expected to serve as the event headliner.

[9] A light heavyweight bout between Shamil Gamzatov and Da Un Jung was scheduled for the preliminary portion of the card.

[10] However, Gamzatov was removed from the bout on March 24 due to alleged visa issues and replaced by William Knight.

[12] However, Malecki pulled out a week before the contest due to undisclosed reasons and was replaced by promotional newcomer Erin Blanchfield.